The Sodium Channel β3-Subunit Induces Multiphasic Gating in Na(V)1.3 and Affects Fast Inactivation via Distinct Intracellular Regions

Electrical excitability in neurons depends on the activity of membrane-bound voltage gated sodium channels (Na(v)) that are assembled from an ion conducting α-subunit and often auxiliary β-subunits. The α-subunit isoform Na(v)1.3 occurs in peripheral neurons together with the Na(v) β3-subunit, both...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cusdin, Fiona S., Nietlispach, Daniel, Maman, Joseph, Dale, Timothy J., Powell, Andrew J., Clare, Jeffrey J., Jackson, Antony P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963402/
https://ncbi.nlm.nih.gov/pubmed/20675377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.114058
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados