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The importance of serine 161 in the sodium channel β3 subunit for modulation of Na(v)1.2 gating

Voltage-gated sodium (Na) channels contribute to the regulation of cellular excitability due to their role in the generation and propagation of action potentials. They are composed of a pore-forming α subunit and are modulated by at least two of four distinct β subunits (β1–4). Recent studies have i...

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Main Authors: Merrick, Ellen C., Kalmar, Christopher L., Snyder, Sandy L., Cusdin, Fiona S., Yu, Ester J., Sando, Julianne J., Isakson, Brant E., Jackson, Antony P., Patel, Manoj K.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891377/
https://ncbi.nlm.nih.gov/pubmed/19806359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-009-0739-y
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