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Both Transcriptional Regulation and Translational Control of ATF4 Are Central to the Integrated Stress Response
In response to different environmental stresses, phosphorylation of eIF2 (eIF2∼P) represses global translation coincident with preferential translation of ATF4. ATF4 is a transcriptional activator of the integrated stress response, a program of gene expression involved in metabolism, nutrient uptake...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963398/ https://ncbi.nlm.nih.gov/pubmed/20732869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.167213 |
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