SIRT1 Activation by Small Molecules: KINETIC AND BIOPHYSICAL EVIDENCE FOR DIRECT INTERACTION OF ENZYME AND ACTIVATOR

SIRT1 is a protein deacetylase that has emerged as a therapeutic target for the development of activators to treat diseases of aging. SIRT1-activating compounds (STACs) have been developed that produce biological effects consistent with direct SIRT1 activation. At the molecular level, the mechanism...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dai, Han, Kustigian, Lauren, Carney, David, Case, April, Considine, Thomas, Hubbard, Basil P., Perni, Robert B., Riera, Thomas V., Szczepankiewicz, Bruce, Vlasuk, George P., Stein, Ross L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963390/
https://ncbi.nlm.nih.gov/pubmed/20702418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.133892
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados