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Characterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1

Histone modification is well established as a fundamental mechanism driving the regulation of transcription, replication, and DNA repair through the control of chromatin structure. Likewise, it is apparent that incorrect targeting of histone modifications contributes to misregulated gene expression...

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Autori principali: Odho, Zain, Southall, Stacey M., Wilson, Jon R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963364/
https://ncbi.nlm.nih.gov/pubmed/20716525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.159921
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