Spectroscopic Studies of GSK3β Phosphorylation of the Neuronal Tau Protein and Its Interaction with the N-terminal Domain of Apolipoprotein E

Alzheimer disease neurons are characterized by extraneuronal plaques formed by aggregated amyloid-β peptide and by intraneuronal tangles composed of fibrillar aggregates of the microtubule-associated Tau protein. Tau is mostly found in a hyperphosphorylated form in these tangles. Glycogen synthase k...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Leroy, Arnaud, Landrieu, Isabelle, Huvent, Isabelle, Legrand, Dominique, Codeville, Bernadette, Wieruszeski, Jean-Michel, Lippens, Guy
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2010
נושאים:
Molecular Biophysics
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963357/
https://ncbi.nlm.nih.gov/pubmed/20679343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149419
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