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Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions.

Oxidatively modified lipoproteins have been implicated in atherogenesis, but the mechanisms that promote oxidation in vivo have not been identified. Myeloperoxidase, a heme protein secreted by activated macrophages, generates reactive intermediates that oxidize lipoproteins in vitro. To explore the...

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書誌詳細
出版年:J Clin Invest
主要な著者: Daugherty, A, Dunn, J L, Rateri, D L, Heinecke, J W
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296328/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040285/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117342
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