Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions.

Oxidation of low density lipoprotein (LDL) enhances its atherogenicity, and inhibition of such oxidation decreases the rate of progression of atherosclerotic lesions. The mechanism of LDL oxidation in vivo remains uncertain, but in vitro studies have suggested that cellular lipoxygenases may play a...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ylä-Herttuala, S, Rosenfeld, M E, Parthasarathy, S, Glass, C K, Sigal, E, Witztum, J L, Steinberg, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54661/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1698286/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.18.6959
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