Macrophage-derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low-density lipoproteins, and contain oxidation-specific lipid-protein adducts.

Documenti analoghi

• Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.
  di: Ylä-Herttuala, S, et al.
  Pubblicazione: (1989)
• Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts.
  di: Ylä-Herttuala, S, et al.
  Pubblicazione: (1991)
• Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions.
  di: Ylä-Herttuala, S, et al.
  Pubblicazione: (1990)
• Low density lipoprotein undergoes oxidative modification in vivo.
  di: Palinski, W, et al.
  Pubblicazione: (1989)
• Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid–protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins
  di: Hörkkö, Sohvi, et al.
  Pubblicazione: (1999)