Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions.

Oxidatively modified lipoproteins have been implicated in atherogenesis, but the mechanisms that promote oxidation in vivo have not been identified. Myeloperoxidase, a heme protein secreted by activated macrophages, generates reactive intermediates that oxidize lipoproteins in vitro. To explore the...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Daugherty, A, Dunn, J L, Rateri, D L, Heinecke, J W
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296328/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8040285/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117342
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