Estrogen Negatively Regulates the Pro-apoptotic Function of Mixed Lineage Kinase 3 in Estrogen Receptor Positive Breast Cancer

Estrogen stimulates growth and inhibits apoptosis of breast cancer cells via genomic and non-genomic actions. However, the detailed mechanism by which estrogen inhibits the pro-apoptotic pathways that might impede the normal homeostasis and action of chemotherapeutic drugs in breast cancer cells is...

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Main Authors: Rangasamy, Velusamy, Mishra, Rajakishore, Mehrotra, Suneet, Sondarva, Gautam, Ray, Rajarshi S., Rao, Arundhati, Chatterjee, Malay, Rana, Basabi, Rana, Ajay
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963191/
https://ncbi.nlm.nih.gov/pubmed/20145118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3492
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