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Mixed Lineage Kinase 3 Modulates β-Catenin Signaling in Cancer Cells
Expression of β-catenin is strictly regulated in normal cells via the glycogen synthase kinase 3β (GSK3β)- adenomatous polyposis coli-axin-mediated degradation pathway. Mechanisms leading to inactivation of this pathway (example: activation of Wnt/β-catenin signaling or mutations of members of the d...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199493/ https://ncbi.nlm.nih.gov/pubmed/21880738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.298943 |
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