Mixed Lineage Kinase 3 Modulates β-Catenin Signaling in Cancer Cells

Expression of β-catenin is strictly regulated in normal cells via the glycogen synthase kinase 3β (GSK3β)- adenomatous polyposis coli-axin-mediated degradation pathway. Mechanisms leading to inactivation of this pathway (example: activation of Wnt/β-catenin signaling or mutations of members of the d...

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Main Authors: Thylur, Ramesh P., Senthivinayagam, Subramanian, Campbell, Edward M., Rangasamy, Velusamy, Thorenoor, Nithyananda, Sondarva, Gautam, Mehrotra, Suneet, Mishra, Prajna, Zook, Erin, Le, Phong T., Rana, Ajay, Rana, Basabi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199493/
https://ncbi.nlm.nih.gov/pubmed/21880738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.298943
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