Caspase-mediated Cleavage of β-Catenin Precedes Drug-induced Apoptosis in Resistant Cancer Cells

A delicate balance between cell death and survival pathways maintains normal physiology, which is altered in many cancers, shifting the balance toward increased survival. Several studies have established a close connection between the Wnt/β-catenin pathway and tumorigenesis, aberrant activation of w...

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Autors principals: Senthivinayagam, Subramanian, Mishra, Prajna, Paramasivam, Suresh Kanna, Yallapragada, Srinivas, Chatterjee, Malay, Wong, Lucas, Rana, Ajay, Rana, Basabi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Mechanisms of Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679459/
https://ncbi.nlm.nih.gov/pubmed/19289465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900248200
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