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Peroxisome proliferator-activated receptor gamma ligand-mediated apoptosis of hepatocellular carcinoma cells depends upon modulation of PI3Kinase pathway independent of Akt

BACKGROUND: Ligands of Peroxisome proliferator-activated receptor gamma (PPARγ) can inhibit growth and promote apoptosis in various cancer cells, and thus have the potential to be utilized as anticancer drugs. This potential however, has been seriously challenged by observations that they can lead t...

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Detalhes bibliográficos
Main Authors: Mishra, Prajna, Paramasivam, Suresh K, Thylur, Ramesh P, Rana, Ajay, Rana, Basabi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009957/
https://ncbi.nlm.nih.gov/pubmed/21144036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-5-20
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