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TRAF2-MLK3 interaction is essential for TNF-α-induced MLK3 activation
Mixed Lineage Kinase 3 (MLK3) is a mitogen-activated protein kinase kinase kinase (MAPKKK) that is activated by Tumor Necrosis Factor-α (TNF-α) and specifically activates c-Jun N-terminal kinase (JNK) upon TNF-α stimulation. The mechanism by which TNF-α activates MLK3 is still not known. TNF recepto...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801772/ https://ncbi.nlm.nih.gov/pubmed/19918265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2009.125 |
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