TRAF2-MLK3 interaction is essential for TNF-α-induced MLK3 activation

Mixed Lineage Kinase 3 (MLK3) is a mitogen-activated protein kinase kinase kinase (MAPKKK) that is activated by Tumor Necrosis Factor-α (TNF-α) and specifically activates c-Jun N-terminal kinase (JNK) upon TNF-α stimulation. The mechanism by which TNF-α activates MLK3 is still not known. TNF recepto...

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Main Authors: Sondarva, Gautam, Kundu, Chanakya N., Mehrotra, Suneet, Mishra, Rajakishore, Rangasamy, Velusamy, Sathyanarayana, Pradeep, Ray, Rajarshi S., Rana, Basabi, Rana, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801772/
https://ncbi.nlm.nih.gov/pubmed/19918265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2009.125
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