Glycogen Synthase Kinase-3β Induces Neuronal Cell Death via Direct Phosphorylation of Mixed Lineage Kinase 3()

Mixed lineage kinase 3 (MLK3) is a mitogen-activated protein kinase kinase kinase member that activates the c-Jun N-terminal kinase (JNK) pathway. Aberrant activation of MLK3 has been implicated in neurodegenerative diseases. Similarly, glycogen synthase kinase (GSK)-3β has also been shown to activa...

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Publicado en:J Biol Chem
Autores principales: Mishra, Rajakishore, Barthwal, Manoj K., Sondarva, Gautam, Rana, Basabi, Wong, Lucas, Chatterjee, Malay, Woodgett, James R., Rana, Ajay
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323256/
https://ncbi.nlm.nih.gov/pubmed/17711861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705895200
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