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Local encoding of computationally designed enzyme activity
One aim of computational protein design is to introduce novel enzyme activity into proteins of known structure by predicting mutations that stabilize transition states. Previously we have shown that it is possible to introduce triose phosphate isomerase activity into the ribose-binding protein of Es...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2006
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2963085/ https://ncbi.nlm.nih.gov/pubmed/17196220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.12.002 |
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