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Increased Expression of the E3 Ubiquitin Ligase RNF5 Is Associated with Decreased Survival in Breast Cancer

The selective ubiquitination of proteins by ubiquitin E3 ligases plays an important regulatory role in control of cell differentiation, growth, and transformation and their dysregulation is often associated with pathologic outcomes, including tumorigenesis. RNF5 is an E3 ubiquitin ligase that has be...

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Autori principali: Bromberg, Kenneth D., Kluger, Harriet M., Delaunay, Agnes, Abbas, Sabiha, DiVito, Kyle A., Krajewski, Stan, Ronai, Ze’ev
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962863/
https://ncbi.nlm.nih.gov/pubmed/17804730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-0045
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