Convergence of Presenilin- and Tau-Mediated Pathways on Axonal Trafficking and Neuronal Function

Alzheimer's disease (AD) is a significant and growing health problem in the aging population. Although definitive mechanisms of pathogenesis remain elusive, genetic and histological clues have implicated the proteins presenilin (PS) and tau as key players in AD development. PS mutations lead to...

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Détails bibliographiques
Auteurs principaux: Peethumnongsin, Erica, Yang, Li, Kallhoff-Muñoz, Verena, Hu, Lingyun, Takashima, Akihiko, Pautler, Robia G., Zheng, Hui
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2010
Sujets:
Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962595/
https://ncbi.nlm.nih.gov/pubmed/20926667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1964-10.2010
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