Convergence of Presenilin- and Tau-Mediated Pathways on Axonal Trafficking and Neuronal Function

Alzheimer's disease (AD) is a significant and growing health problem in the aging population. Although definitive mechanisms of pathogenesis remain elusive, genetic and histological clues have implicated the proteins presenilin (PS) and tau as key players in AD development. PS mutations lead to...

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Detalhes bibliográficos
Main Authors: Peethumnongsin, Erica, Yang, Li, Kallhoff-Muñoz, Verena, Hu, Lingyun, Takashima, Akihiko, Pautler, Robia G., Zheng, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962595/
https://ncbi.nlm.nih.gov/pubmed/20926667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1964-10.2010
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