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Increased Human Wildtype Tau Attenuates Axonal Transport Deficits Caused by Loss of APP in Mouse Models

Amyloid precursor protein (APP) is implicated in axonal elongation, synaptic plasticity, and axonal transport. However, the role of APP on axonal transport in conjunction with the microtubule associated protein tau continues to be debated. Here we measured in vivo axonal transport in APP knockout mi...

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Detalhes bibliográficos
Main Authors: Smith, Karen D.B., Peethumnongsin, Erica, Lin, Han, Zheng, Hui, Pautler, Robia G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927830/
https://ncbi.nlm.nih.gov/pubmed/20798780
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