Extracellular Microfibrils Control Osteoblast-supported Osteoclastogenesis by Restricting TGFβ Stimulation of RANKL Production

Mutations in fibrillin-1 or fibrillin-2, the major structural components of extracellular microfibrils, cause pleiotropic manifestations in Marfan syndrome and congenital contractural arachnodactyly, respectively. We recently found that fibrillin-1 and fibrillin-2 control bone formation by regulatin...

Full description

Saved in:
Bibliographic Details
Main Authors: Nistala, Harikiran, Lee-Arteaga, Sui, Smaldone, Silvia, Siciliano, Gabriella, Ramirez, Francesco
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962511/
https://ncbi.nlm.nih.gov/pubmed/20729550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.125328
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items