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Generation of Fbn1 conditional null mice implicates the extracellular microfibrils in osteoprogenitor recruitment
Loss-of-function experiments in mice have yielded invaluable mechanistic insights into the pathogenesis of Marfan syndrome (MFS) and implicitly, into the multiple roles fibrillin-1 microfibrils play in the developing and adult organism. Unfortunately, neonatal death from aortic complications of mice...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3405165/ https://ncbi.nlm.nih.gov/pubmed/22374917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22022 |
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