Generation of Fbn1 conditional null mice implicates the extracellular microfibrils in osteoprogenitor recruitment

Loss-of-function experiments in mice have yielded invaluable mechanistic insights into the pathogenesis of Marfan syndrome (MFS) and implicitly, into the multiple roles fibrillin-1 microfibrils play in the developing and adult organism. Unfortunately, neonatal death from aortic complications of mice...

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Главные авторы: Cook, Jason R., Smaldone, Silvia, Cozzolino, Carmine, del Solar, Maria, Lee-Arteaga, Sui, Nistala, Harikiran, Ramirez, Francesco
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405165/
https://ncbi.nlm.nih.gov/pubmed/22374917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22022
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