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Regulation of the AGS3·Gα(i) Signaling Complex by a Seven-transmembrane Span Receptor

G-protein signaling modulators (GPSM) play diverse functional roles through their interaction with G-protein subunits. AGS3 (GPSM1) contains four G-protein regulatory motifs (GPR) that directly bind Gα(i) free of Gβγ providing an unusual scaffold for the “G-switch” and signaling complexes, but the m...

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Autores principales: Oner, Sukru Sadik, An, Ningfei, Vural, Ali, Breton, Billy, Bouvier, Michel, Blumer, Joe B., Lanier, Stephen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962495/
https://ncbi.nlm.nih.gov/pubmed/20716524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.138073
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