Distribution of Activator of G-Protein Signaling 3 within the Aggresomal Pathway: Role of Specific Residues in the Tetratricopeptide Repeat Domain and Differential Regulation by the AGS3 Binding Partners Giα and Mammalian Inscuteable

AGS3, a receptor-independent activator of G-protein signaling, is involved in unexpected functional diversity for G-protein signaling systems. AGS3 has seven tetratricopeptide (TPR) motifs upstream of four G-protein regulatory (GPR) motifs that serve as docking sites for Giα-GDP. The positioning of...

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Detalhes bibliográficos
Main Authors: Vural, Ali, Oner, Sadik, An, Ningfei, Simon, Violaine, Ma, Dzwokai, Blumer, Joe B., Lanier, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832490/
https://ncbi.nlm.nih.gov/pubmed/20065032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01018-09
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