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ATP-dependent Mechanism Protects Spectrin against Glycation in Human Erythrocytes

Human erythrocytes are continuously exposed to glucose, which reacts with the amino terminus of the β-chain of hemoglobin (Hb) to form glycated Hb, HbA1c, levels of which increase with the age of the circulating cell. In contrast to extensive insights into glycation of hemoglobin, little is known ab...

詳細記述

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書誌詳細
主要な著者: Manno, Sumie, Mohandas, Narla, Takakuwa, Yuichi
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962492/
https://ncbi.nlm.nih.gov/pubmed/20724481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.126896
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