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ATP-dependent Mechanism Protects Spectrin against Glycation in Human Erythrocytes

Human erythrocytes are continuously exposed to glucose, which reacts with the amino terminus of the β-chain of hemoglobin (Hb) to form glycated Hb, HbA1c, levels of which increase with the age of the circulating cell. In contrast to extensive insights into glycation of hemoglobin, little is known ab...

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Detalhes bibliográficos
Main Authors: Manno, Sumie, Mohandas, Narla, Takakuwa, Yuichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962492/
https://ncbi.nlm.nih.gov/pubmed/20724481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.126896
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