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Membrane Peroxidation and Methemoglobin Formation are Both Necessary for Band 3 Clustering: Mechanistic Insights into Human Erythrocyte Senescence

Oxidative damage and clustering of band 3 in the membrane have been implicated in the removal of senescent human erythrocytes from the circulation at the end of their 120-day life span. However, the biochemical and mechanistic events leading to band 3 cluster formation have yet to be fully defined....

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Detalhes bibliográficos
Main Authors: Arashiki, Nobuto, Kimata, Naoki, Manno, Sumie, Mohandas, Narla, Takakuwa, Yuichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914982/
https://ncbi.nlm.nih.gov/pubmed/23889086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400405p
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