ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia

Phosphatidylserine is localized exclusively to the inner leaflet of the membrane lipid bilayer of most cells, including erythrocytes. This asymmetric distribution is critical for the survival of erythrocytes in circulation since externalized phosphatidylserine is a phagocytic signal for splenic macr...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Arashiki, Nobuto, Takakuwa, Yuichi, Mohandas, Narla, Hale, John, Yoshida, Kenichi, Ogura, Hiromi, Utsugisawa, Taiju, Ohga, Shouichi, Miyano, Satoru, Ogawa, Seishi, Kojima, Seiji, Kanno, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004368/
https://ncbi.nlm.nih.gov/pubmed/26944472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.142273
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