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ATP-dependent Mechanism Protects Spectrin against Glycation in Human Erythrocytes

Human erythrocytes are continuously exposed to glucose, which reacts with the amino terminus of the β-chain of hemoglobin (Hb) to form glycated Hb, HbA1c, levels of which increase with the age of the circulating cell. In contrast to extensive insights into glycation of hemoglobin, little is known ab...

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Autori principali: Manno, Sumie, Mohandas, Narla, Takakuwa, Yuichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962492/
https://ncbi.nlm.nih.gov/pubmed/20724481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.126896
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