RNA-binding Protein Muscleblind-like 3 (MBNL3) Disrupts Myocyte Enhancer Factor 2 (Mef2) β-Exon Splicing

Mammalian MBNL (muscleblind-like) proteins are regulators of alternative splicing and have been implicated in myotonic dystrophy, the most common form of adult onset muscular dystrophy. MBNL3 functions as an inhibitor of muscle differentiation and is expressed in proliferating muscle precursor cells...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee, Kyung-Soon, Cao, Yi, Witwicka, Hanna E., Tom, Susan, Tapscott, Stephen J., Wang, Edith H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
Gene Regulation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962477/
https://ncbi.nlm.nih.gov/pubmed/20709755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.124255
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