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An Exceptionally Potent Inducer of Cytoprotective Enzymes: ELUCIDATION OF THE STRUCTURAL FEATURES THAT DETERMINE INDUCER POTENCY AND REACTIVITY WITH Keap1
The Keap1/Nrf2/ARE pathway controls a network of cytoprotective genes that defend against the damaging effects of oxidative and electrophilic stress, and inflammation. Induction of this pathway is a highly effective strategy in combating the risk of cancer and chronic degenerative diseases, includin...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2962473/ https://ncbi.nlm.nih.gov/pubmed/20801881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.163485 |
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