Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

Antzeko izenburuak

• Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers
  nork: Wakabayashi, Nobunao, et al.
  Argitaratua: (2004)
• The Role of Sulfhydryl Reactivity of Small Molecules for the Activation of the KEAP1/NRF2 Pathway and the Heat Shock Response
  nork: Dinkova-Kostova, Albena T.
  Argitaratua: (2012)
• The Role of Sulfhydryl Reactivity of Small Molecules for the Activation of the KEAP1/NRF2 Pathway and the Heat Shock Response
  nork: Albena T. Dinkova-Kostova
  Argitaratua: (2012-01-01)
• Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
  nork: Itoh, Ken, et al.
  Argitaratua: (1999)
• Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants()
  nork: Dinkova-Kostova, Albena T., et al.
  Argitaratua: (2017)