A carregar...

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

Coordinate induction of phase 2 proteins and elevation of glutathione protect cells against the toxic and carcinogenic effects of electrophiles and oxidants. All inducers react covalently with thiols at rates that are closely related to their potencies. Inducers disrupt the cytoplasmic complex betwe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dinkova-Kostova, Albena T., Holtzclaw, W. David, Cole, Robert N., Itoh, Ken, Wakabayashi, Nobunao, Katoh, Yasutake, Yamamoto, Masayuki, Talalay, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129367/
https://ncbi.nlm.nih.gov/pubmed/12193649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172398899
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!