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Regulation of Human Cytidine Triphosphate Synthetase 2 by Phosphorylation
Cytidine triphosphate synthetase (CTPS) is the rate-limiting enzyme in de novo CTP synthesis and is required for the formation of RNA, DNA, and phospholipids. This study determined the kinetic properties of the individual human CTPS isozymes (hCTPS1 and hCTPS2) and regulation through substrate conce...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2962471/ https://ncbi.nlm.nih.gov/pubmed/20739275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178566 |
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