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Regulation of Human Cytidine Triphosphate Synthetase 2 by Phosphorylation
Cytidine triphosphate synthetase (CTPS) is the rate-limiting enzyme in de novo CTP synthesis and is required for the formation of RNA, DNA, and phospholipids. This study determined the kinetic properties of the individual human CTPS isozymes (hCTPS1 and hCTPS2) and regulation through substrate conce...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2962471/ https://ncbi.nlm.nih.gov/pubmed/20739275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178566 |
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