Regulation of Human Cytidine Triphosphate Synthetase 2 by Phosphorylation

Cytidine triphosphate synthetase (CTPS) is the rate-limiting enzyme in de novo CTP synthesis and is required for the formation of RNA, DNA, and phospholipids. This study determined the kinetic properties of the individual human CTPS isozymes (hCTPS1 and hCTPS2) and regulation through substrate conce...

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Main Authors: Kassel, Karen M., Au, Da Ryung, Higgins, Matthew J., Hines, Maria, Graves, Lee M.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2010
主題:
Enzymology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962471/
https://ncbi.nlm.nih.gov/pubmed/20739275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178566
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