Reduction of Natural Adenovirus Tropism to Mouse Liver by Fiber-Shaft Exchange in Combination with both CAR- and αv Integrin-Binding Ablation

The primary receptor, the coxsackievirus and adenovirus receptor (CAR), and the secondary receptor, αv integrins, are the tropism determinants of adenovirus (Ad) type 5. Inhibition of the interaction of both the fiber with CAR and the penton base with the αv integrin appears to be crucial to the dev...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Koizumi, Naoya, Mizuguchi, Hiroyuki, Sakurai, Fuminori, Yamaguchi, Teruhide, Watanabe, Yoshiteru, Hayakawa, Takao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2003
Gaiak:
Gene Therapy
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC296053/
https://ncbi.nlm.nih.gov/pubmed/14645563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13062-13072.2003
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