Reduction of Natural Adenovirus Tropism to Mouse Liver by Fiber-Shaft Exchange in Combination with both CAR- and αv Integrin-Binding Ablation

The primary receptor, the coxsackievirus and adenovirus receptor (CAR), and the secondary receptor, αv integrins, are the tropism determinants of adenovirus (Ad) type 5. Inhibition of the interaction of both the fiber with CAR and the penton base with the αv integrin appears to be crucial to the dev...

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Бібліографічні деталі

Опубліковано в::	J Virol
Автори:	Koizumi, Naoya, Mizuguchi, Hiroyuki, Sakurai, Fuminori, Yamaguchi, Teruhide, Watanabe, Yoshiteru, Hayakawa, Takao
Формат:	Artigo
Мова:	Inglês
Опубліковано:	American Society for Microbiology (ASM) 2003
Предмети:	Gene Therapy
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296053/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14645563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.24.13062-13072.2003
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