Reduction of Natural Adenovirus Tropism to Mouse Liver by Fiber-Shaft Exchange in Combination with both CAR- and αv Integrin-Binding Ablation

The primary receptor, the coxsackievirus and adenovirus receptor (CAR), and the secondary receptor, αv integrins, are the tropism determinants of adenovirus (Ad) type 5. Inhibition of the interaction of both the fiber with CAR and the penton base with the αv integrin appears to be crucial to the dev...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Koizumi, Naoya, Mizuguchi, Hiroyuki, Sakurai, Fuminori, Yamaguchi, Teruhide, Watanabe, Yoshiteru, Hayakawa, Takao
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Gene Therapy
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC296053/
https://ncbi.nlm.nih.gov/pubmed/14645563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.24.13062-13072.2003
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares