Redox Regulation of Sirtuin-1 by S-Glutathiolation

Sirtuin-1 (SIRT1) is an NAD(+)-dependent protein deacetylase that is sensitive to oxidative signals. Our purpose was to determine whether SIRT1 activity is sensitive to the low molecular weight nitrosothiol, S-nitrosoglutathione (GSNO), which can transduce oxidative signals into physiological respon...

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Detalhes bibliográficos
Main Authors: Zee, Rebecca S., Yoo, Chris B., Pimentel, David R., Perlman, David H., Burgoyne, Joseph R., Hou, Xiuyun, McComb, Mark E., Costello, Catherine E., Cohen, Richard A., Bachschmid, Markus M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959181/
https://ncbi.nlm.nih.gov/pubmed/20392170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3251
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