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Chemistry of the Cysteine Sensors in Kelch-Like ECH-Associated Protein 1

The protein Kelch-like ECH-associated protein 1 (Keap1) is a cysteine-rich regulatory and scaffold protein. Human Keap1 contains 27 cysteines. Some of these cysteines are believed to mediate derepression of the transcription factor nuclear factor (erythroid-derived 2)-like 2 (Nrf2), which subsequent...

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Detalhes bibliográficos
Main Authors: Holland, Ryan, Fishbein, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959180/
https://ncbi.nlm.nih.gov/pubmed/20486763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3273
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