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Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome

Chromatin structure is epigenetically altered via covalent modifications of histones to allow for heritable gene regulation without altering the nucleotide sequence. Multiple lines of evidence from rodents have established a role for epigenetic remodeling in regulating gene transcription in response...

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Bibliografiske detaljer
Main Authors: Aagaard-Tillery, Kjersti M, Grove, Kevin, Bishop, Jacalyn, Ke, Xingrao, Fu, Qi, McKnight, Robert, Lane, Robert H
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959100/
https://ncbi.nlm.nih.gov/pubmed/18515302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JME-08-0025
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