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Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome

Chromatin structure is epigenetically altered via covalent modifications of histones to allow for heritable gene regulation without altering the nucleotide sequence. Multiple lines of evidence from rodents have established a role for epigenetic remodeling in regulating gene transcription in response...

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Detalhes bibliográficos
Main Authors: Aagaard-Tillery, Kjersti M, Grove, Kevin, Bishop, Jacalyn, Ke, Xingrao, Fu, Qi, McKnight, Robert, Lane, Robert H
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959100/
https://ncbi.nlm.nih.gov/pubmed/18515302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JME-08-0025
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