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A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates
In nonhuman primates, we previously demonstrated that a maternal high-fat diet (MHFD) induces fetal nonalcoholic fatty liver disease (NAFLD) and alters the fetal metabolome. These changes are accompanied by altered acetylation of histone H3 (H3K14ac). However, the mechanism behind this alteration in...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Federation of American Societies for Experimental Biology
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3509051/ https://ncbi.nlm.nih.gov/pubmed/22982377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-212878 |
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