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Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates

Maternal obesity is thought to increase the offspring’s risk of juvenile obesity and metabolic diseases; however, the mechanism(s) whereby excess maternal nutrition affects fetal development remain poorly understood. Here, we investigated in nonhuman primates the effect of chronic high-fat diet (HFD...

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Detalhes bibliográficos
Main Authors: McCurdy, Carrie E., Bishop, Jacalyn M., Williams, Sarah M., Grayson, Bernadette E., Smith, M. Susan, Friedman, Jacob E., Grove, Kevin L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631287/
https://ncbi.nlm.nih.gov/pubmed/19147984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32661
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