p27(Kip1 )deficiency promotes prostate carcinogenesis but does not affect the efficacy of retinoids in suppressing the neoplastic process

BACKGROUND: p27 is a cell cycle suppressor gene, whose protein is a negative regulator of cyclin/cdk complexes. p27 is also a potential target of retinoids in cancer prevention studies. In benign prostate hyperplasia (BPH), and in most carcinomas, p27(Kip1 )is down-regulated, suggesting its potentia...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Taylor, Winna, Mathias, Amanda, Ali, Arshia, Ke, Hengning, Stoynev, Nikolay, Shilkaitis, Anne, Green, Albert, Kiyokawa, Hiroaki, Christov, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958951/
https://ncbi.nlm.nih.gov/pubmed/20932324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-541
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados