Retinoids induce cellular senescence in breast cancer cells by RAR-β dependent and independent pathways: Potential clinical implications (Review)

Por SHILKAITIS, ANNE, GREEN, ALBERT, CHRISTOV, KONSTANTIN
Publicado no Int J Oncol (2015)

Cdk2-Null Mice Are Resistant to ErbB-2-Induced Mammary Tumorigenesis

Por Ray, Dipankar, Terao, Yasuhisa, Christov, Konstantin, Kaldis, Philipp, Kiyokawa, Hiroaki
Publicado em 2011

Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism

Por Shilkaitis, Anne, Green, Albert, Punj, Vasu, Steele, Vernon, Lubet, Ronald, Christov, Konstantin
Publicado em 2005

Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence

Por Zou, Xianghong, Ray, Dipankar, Aziyu, Aileen, Christov, Konstantin, Boiko, Alexander D., Gudkov, Andrei V., Kiyokawa, Hiroaki
Publicado em 2002

MEN1-tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2

Por Gillam, Mary P., Nimbalkar, Dipali, Sun, Limin, Christov, Konstantin, Ray, Dipankar, Kaldis, Philipp, Liu, Xianpeng, Kiyokawa, Hiroaki
Publicado em 2014

p27(Kip1 )deficiency promotes prostate carcinogenesis but does not affect the efficacy of retinoids in suppressing the neoplastic process

Por Taylor, Winna, Mathias, Amanda, Ali, Arshia, Ke, Hengning, Stoynev, Nikolay, Shilkaitis, Anne, Green, Albert, Kiyokawa, Hiroaki, Christov, Konstantin
Publicado em 2010

Disruption of Growth Hormone Signaling Retards Prostate Carcinogenesis in the Probasin/TAg Rat

Por Wang, Zhuohua, Luque, Raul M., Kineman, Rhonda D., Ray, Vera H., Christov, Konstantin T., Lantvit, Daniel D., Shirai, Tomoyuki, Hedayat, Samad, Unterman, Terry G., Bosland, Maarten C., Prins, Gail S., Swanson, Steven M.
Publicado em 2008

MADD Knock-Down Enhances Doxorubicin and TRAIL Induced Apoptosis in Breast Cancer Cells

Por Turner, Andrea, Li, Liang-Cheng, Pilli, Tania, Qian, Lixia, Wiley, Elizabeth Louise, Setty, Suman, Christov, Konstantin, Ganesh, Lakshmy, Maker, Ajay V., Li, Peifeng, Kanteti, Prasad, Das Gupta, Tapas K., Prabhakar, Bellur S.
Publicado em 2013

Methyl-Substituted Conformationally Constrained Rexinoid Agonists for the Retinoid X Receptors Demonstrate Improved Efficacy for Cancer Therapy and Prevention

Por Desphande, Anil, Xia, Gang, Boerma, LeeAnn J., Vines, Kimberly K, Atigadda, Venkatram R., Lobo-Ruppert, Susan, Grubbs, Clinton J., Moeinpour, Fariba L, Smith, Craig D., Christov, Konstantin, Brouillette, Wayne J., Muccio, Donald D.
Publicado no Bioorg Med Chem (2013)