Retinoids induce cellular senescence in breast cancer cells by RAR-β dependent and independent pathways: Potential clinical implications (Review)

by SHILKAITIS, ANNE, GREEN, ALBERT, CHRISTOV, KONSTANTIN
Published in Int J Oncol (2015)

Cdk2-Null Mice Are Resistant to ErbB-2-Induced Mammary Tumorigenesis

by Ray, Dipankar, Terao, Yasuhisa, Christov, Konstantin, Kaldis, Philipp, Kiyokawa, Hiroaki
Published 2011

Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism

by Shilkaitis, Anne, Green, Albert, Punj, Vasu, Steele, Vernon, Lubet, Ronald, Christov, Konstantin
Published 2005

Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence

by Zou, Xianghong, Ray, Dipankar, Aziyu, Aileen, Christov, Konstantin, Boiko, Alexander D., Gudkov, Andrei V., Kiyokawa, Hiroaki
Published 2002

MEN1-tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2

by Gillam, Mary P., Nimbalkar, Dipali, Sun, Limin, Christov, Konstantin, Ray, Dipankar, Kaldis, Philipp, Liu, Xianpeng, Kiyokawa, Hiroaki
Published 2014

p27(Kip1 )deficiency promotes prostate carcinogenesis but does not affect the efficacy of retinoids in suppressing the neoplastic process

by Taylor, Winna, Mathias, Amanda, Ali, Arshia, Ke, Hengning, Stoynev, Nikolay, Shilkaitis, Anne, Green, Albert, Kiyokawa, Hiroaki, Christov, Konstantin
Published 2010

Disruption of Growth Hormone Signaling Retards Prostate Carcinogenesis in the Probasin/TAg Rat

by Wang, Zhuohua, Luque, Raul M., Kineman, Rhonda D., Ray, Vera H., Christov, Konstantin T., Lantvit, Daniel D., Shirai, Tomoyuki, Hedayat, Samad, Unterman, Terry G., Bosland, Maarten C., Prins, Gail S., Swanson, Steven M.
Published 2008

MADD Knock-Down Enhances Doxorubicin and TRAIL Induced Apoptosis in Breast Cancer Cells

by Turner, Andrea, Li, Liang-Cheng, Pilli, Tania, Qian, Lixia, Wiley, Elizabeth Louise, Setty, Suman, Christov, Konstantin, Ganesh, Lakshmy, Maker, Ajay V., Li, Peifeng, Kanteti, Prasad, Das Gupta, Tapas K., Prabhakar, Bellur S.
Published 2013

Methyl-Substituted Conformationally Constrained Rexinoid Agonists for the Retinoid X Receptors Demonstrate Improved Efficacy for Cancer Therapy and Prevention

by Desphande, Anil, Xia, Gang, Boerma, LeeAnn J., Vines, Kimberly K, Atigadda, Venkatram R., Lobo-Ruppert, Susan, Grubbs, Clinton J., Moeinpour, Fariba L, Smith, Craig D., Christov, Konstantin, Brouillette, Wayne J., Muccio, Donald D.
Published in Bioorg Med Chem (2013)