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Retinoids induce cellular senescence in breast cancer cells by RAR-β dependent and independent pathways: Potential clinical implications (Review)

Most studies on cellular senescence (CS) have been performed in vitro by employing cytotoxic agents, irradiation, chromatin and telomerase modulators or by activating certain oncogenes. All these approaches usually lead to DNA damage, gene instability and/or chromatin alterations that primarily affe...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: SHILKAITIS, ANNE, GREEN, ALBERT, CHRISTOV, KONSTANTIN
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485653/
https://ncbi.nlm.nih.gov/pubmed/25997921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.3013
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