Lipid-induced changes in intracellular iron homeostasis in vitro and in vivo.

Iron promotes cellular damage via its capacity to catalyze hydroxyl radical formation and by peroxidation of unsaturated lipids. The major cellular iron storage depot, ferritin, acts as a critical antioxidant defense by sequestering unbound or "free" iron, limiting its participation in dam...

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Autores principales: Van Lenten, B J, Prieve, J, Navab, M, Hama, S, Lusis, A J, Fogelman, A M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC295808/
https://ncbi.nlm.nih.gov/pubmed/7738177
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