A new antiinflammatory compound, leumedin, inhibits modification of low density lipoprotein and the resulting monocyte transmigration into the subendothelial space of cocultures of human aortic wall cells.

Eitemau Tebyg

• Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein.
  gan: Navab, M, et al.
  Cyhoeddwyd: (1991)
• Monocyte migration into the subendothelial space of a coculture of adult human aortic endothelial and smooth muscle cells.
  gan: Navab, M, et al.
  Cyhoeddwyd: (1988)
• Interaction of monocytes with cocultures of human aortic wall cells involves interleukins 1 and 6 with marked increases in connexin43 message.
  gan: Navab, M, et al.
  Cyhoeddwyd: (1991)
• Anti-inflammatory HDL becomes pro-inflammatory during the acute phase response. Loss of protective effect of HDL against LDL oxidation in aortic wall cell cocultures.
  gan: Van Lenten, B J, et al.
  Cyhoeddwyd: (1995)
• Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL.
  gan: Ishikawa, K, et al.
  Cyhoeddwyd: (1997)